Medicine Recommendations

Type 2 diabetes mellitus [in combination with metformin]

Type 1 and type 2 diabetes mellitus

Type 1 and type 2 diabetes mellitus

Treatment of diabetes mellitus in adults

Hypothyroidism

Type 1 and type 2 diabetes mellitus

Type 2 diabetes

Add-on treatment for refractory hypothyroidism despite adequate replacement with levothyroxine – new patients.

Liothyronine for the treatment of acute conditions where thyroid replacement is needed rapidly, for a limited period and/or where a drug with shorter half-life is required.

Resistant depression

**This entry is under review**

Liothyronine monotherapy for the management of chronic hypothyroidism – primary and secondary care

Add-on treatment for refractory hypothyroidism – existing patients.

Liothyronine therapy commenced in the private sector

Type 2 diabetes mellitus (NICE NG28)

NICE NG28 - Type 2 diabetes in adults: management

NICE TA664 - For managing overweight and obesity

Type 2 diabetes mellitus

Suitable for initiation in primary care in line with restrictions (see background paragraph)

Reduction in the risk or delay of the onset of type 2 diabetes mellitus in adult, overweight patients with implied Glucose Tolerance and/or increased HbA1C who are at high risk for developing overt type 2 diabetes mellitus and still progressing towards type 2 diabetes mellitus despite implementation of intensive lifestyle change for 3-6 months

Treatment of type 2 diabetes mellitus, particularly in overweight patients, when dietary management and exercise alone does not result in adequate glycaemic control

Acute Gout (as per LSCMMG Guidelines)

Metabolic acidosis and for maintenance treatment against recurrence of metabolic acidosis in adults with chronic renal impairment.